• br ACCEPTED MANUSCRIPT br Another interesting approach to en

  2020-08-18

  

  ACCEPTED MANUSCRIPT Another interesting approach to enhancing anti-PD-1 therapies has been the use of PD-1 receptor-expressing nanovesicle decoys88. Cellular membranes can be engineered into nanoscale vesicles using a membrane extrusion method. One group generated nanovesicles with high levels

• b iframe width height src https www

  2020-08-18

  

  r> UUAUCU CUGAGA-3′), and PLIN3 (5′- CUGUCAAGCAAGGCGU UGA-3′). The full-length Arp3 and ARPC2 genes were obtained by PCR using suitable primers with restriction enzyme cleavage sites appended to overexpress of Arp3 and ARPC2. Arp3 forward primer (5′-CGGGGT ACCCCATGGACAGCCAGGGCAGGAA-3′) and Arp3 rev

• br Imaging and Segmentation br miR

  2020-08-14

  

  Imaging and Segmentation miR-182 ISH was imaged on the Vectra Automated Mul-tispectral Imaging System (PerkinElmer) at the Research Histology and Tissue Imaging Core at UIC. Cores were imaged at 20 magnification and tiled. Images were un-mixed using a spectral library for Vector Red signal crea

• br Materials and methods br Study population

  2020-08-14

  

  2. Materials and methods 2.1. Study population and design We utilized data from the Korean National Health Insurance Service (NHIS) that was collected from January 2002 to December 2015. The Korean health insurance system officially started in 1977 and gradually expanded to the NHIS system t

• br Aspirin affects the characteristics of

  2020-08-12

  

  3.4. Aspirin affects the characteristics of exosomes secreted by lung cancer 2070009-61-7 under hypoxic conditions Since cancer-derived exosomes contribute to TME recruitment and reprogramming, we isolated exosomes from the conditioned medium and characterized A549 exosomes by electron microsco

• br Altered expression of cell cycle regulatory proteins and

  2020-08-12

  

  2.3. Altered expression of AICAR regulatory proteins and activation of the p38 MAP kinase pathway in breast cancer cells after treatment with CTU analogues In view of findings from flow cytometry we evaluated the effect of CTU analogues on the expression of important cell cycle regulatory prot

• br Sigma g glycerol Chemworks Beijing China g propylene glyc

  2020-08-12

  

  (Sigma), 1.5 g glycerol (Chemworks, Beijing, China), 1.5 g propylene glycol (Xilong Chemical Co. Ltd., Guangxi, China), and sterile water were churned and heated to 60 °C. The water phase was added slowly into the oil phase and expanded to 10 mL with sterile water to form the colostrum. Then, the

• br is worth noting that previous studies have

  2020-08-12

  

  is worth noting that previous studies have identified the DGR domain is essential to maintain the interaction of Keap1 and Nrf2 [32,33]. These results therefore suggest that aPKCι competes with Nrf2 to bind with Keap1 through the DLL motif. 3.4. aPKCι promotes GBC 1,2-Distearoyl-sn-glycero-3-PC

• br First we used crystal violet

  2020-08-12

  

  First, we used crystal violet staining to verify whether the recombinant adenoviruses could inhibit PC-3-luc cell  proliferation. Recombinant adenoviruses Ad-VT, Ad-T, Ad-vp3, and Ad-Mock were infected into PC-3-luc cells, separately, and stained with 0.4% crystal violet. As shown in Fig. 3A,

• br Fig Synthesis pathways for analogues

  2020-08-12

  

  Fig. 2. Synthesis pathways for analogues. Analogues 13-16. See text for more details. 3.2. Selected steroid-like SERD candidates promote ER downregulation, bind ER-positive breast tumor ML-162 and block ER-dependent transcription in vitro We used different assays to screen antiestrogen/SERD

• br P vs negative control group

  2020-08-12

  

  P < 0.001, vs. negative control group (untreated cells). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.) considerable capacity for carrying biological information. Currently, extensive studies have indicated the i

• br Fig E ect of CAA on

  2020-08-12

  

  Fig. 9. Effect of CAA45 on autophagy in A549 cell. (A) Cells were plated on coverslips in 24-well plates, treated with CAA45 (0, 0.06, 0.12, 0.25 μM) or Rapa (0.30 μM) for 12 h, then stained with 0.05 mM MDC for 30 min at 37 °C. After washing with PBS, the stained A549 774594-96-6 were immediately

• visualized clear margins and small tumor implants

  2020-08-12

  

  visualized clear margins and small tumor implants in the present study with this probe. Conclusion Claudin-1 is a useful target for NIR antibody-based imaging for visualization of primary and metastatic colorectal tumors for future use in fluorescence-guided surgery. Acknowledgment Autho

• Talanta br Materials and methods br Cell lines and

  2020-08-12

  

   Talanta 199 (2019) 634–642 2. Materials and methods 2.1. Cell lines and buffers The human gastric cancer cell lines BGC-823 and SGC-7901 were used for the selection. The other cell lines used in this study include the human gastric cancer cell lines MGC-803 and MKN28, the human col-orect

• br where S shows the mean values

  2020-08-12

  

  where µS0 shows the mean values of pixels in the area of a cell and S(u, v) pixel value in the area of a cell. Area where σ shows the divergence from the mean distance given by the Distance variable. Mathematically, σ and Distance are computed by the follow-ing equations: where P is the

55 records 2/4 page Previous Next 1234